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Index > Protein center > BCAP31(Gene name) > Human
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  • BCAP31 (Gene name),
  • B-cell receptor-associated protein 31 (Protein name ),  BAP31_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    BCAP31(BAP31;DXS1357E);
    Protein name:
    B-cell receptor-associated protein 31(BCR-associated protein 31;Bap31);
    Alternative:
    Protein CDM;6C6-AG tumor-associated antigen;p28;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer and heterodimer with BCAP29. Binds CASP8 (isoform 9) as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II. Interacts with PTPLB.
    Function:
    May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein Endoplasmic reticulum-Golgi intermediate compartment membrane Multi-pass membrane protein May shuttle between the ER and the intermediate compartment/cis-Golgi complex.
    Protein Attributes:
    Sequence length:
    246
    Sequence:
    50:
    MSLQWTAVAT | FLYAEVFVVL | LLCIPFISPK | RWQKIFKSRL | VELLVSYGNT | 
    100:
    FFVVLIVILV | LLVIDAVREI | RKYDDVTEKV | NLQNNPGAME | HFHMKLFRAQ | 
    150:
    RNLYIAGFSL | LLSFLLRRLV | TLISQQATLL | ASNEAFKKQA | ESASEAAKKY | 
    200:
    MEENDQLKKG | AAVDGGKLDV | GNAEVKLEEE | NRSLKADLQK | LKDELASTKQ | 
    246:
    KLEKAENQVL | AMRKQSEGLT | KEYDRLLEEH | AKLQAAVDGP | MDKKEE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    SMR:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human BCR-associated protein 31
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    E14114h
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    96T
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    ELISA Kit for Human BCR-associated protein 31
    Cat.:
    E14114m
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    Packing:
    96T
    CLIA Kit for Human BCR-associated protein 31
    Cat.:
    U14114h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human BCR-associated protein 31
    Cat.:
    U14114m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human BCR-associated protein 31
    Cat.:
    P14114Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human BCR-associated protein 31
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    P14114Rb-m
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human BCR-associated protein 31
    Monoclonal Antibody for Human BCR-associated protein 31
    Protein for Human BCR-associated protein 31
    Protein for Human BCR-associated protein 31

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A new human gene (DXS1357E) with ubiquitous expression, located in Xq28 adjacent to the adrenoleukodystrophy gene."
      Mosser J. , Sarde C.-O. , Vicaire S. , Yates J.R. , Mandel J.-L.
      Genomics22:469-471(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Molecular cloning and characterization of a transmembrane surface antigen in human cells."
      Li E. , Bestagno M. , Burrone O.
      Eur. J. Biochem.238:631-638(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "The specificity of association of the IgD molecule with the accessory proteins BAP31/BAP29 lies in the IgD transmembrane sequence."
      Adachi T. , Schamel W.W.A. , Kim K.-M. , Watanabe T. , Becker B. , Nielsen P.J. , Reth M.
      EMBO J.15:1534-1541(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: B-cell.
      tissue: Promyelocytic leukemia.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Stomach.
      tissue: Trachea.
    5. 5.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Lung.
      tissue: Pancreas.
    8. 8.
      Eichler E.E. , Lu F. , Shen Y. , Muzny D.M. , Gibbs R.A. , Nelson D.L.
      Submitted (1995-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 121-246
    9. 9.
      "p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum."
      Ng F.W.H. , Nguyen M. , Kwan T. , Branton P.E. , Nicholson D.W. , Cromlish J.A. , Shore G.C.
      J. Cell Biol.139:327-338(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-11;SUBCELLULAR LOCATION;INTERACTION WITH BCL2; BCL2L1 AND CASP8
    10. 10.
      "Export of cellubrevin from the endoplasmic reticulum is controlled by BAP31."
      Annaert W.G. , Becker B. , Kistner U. , Reth M. , Jahn R.
      J. Cell Biol.139:1397-1410(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 80-96 AND 205-214;SUBCELLULAR LOCATION;FUNCTION
    11. 11.
      "Caspase-resistant BAP31 inhibits Fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondria."
      Nguyen M. , Breckenridge D.G. , Ducret A. , Shore G.C.
      Mol. Cell. Biol.20:6731-6740(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF ASP-164 AND ASP-238;ROLE IN APOPTOSIS
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    13. 13.
      "Endoplasmic reticulum membrane-sorting protein of lymphocytes (BAP31) is highly expressed in neurons and discrete endocrine cells."
      Manley H.A. , Lennon V.A.
      J. Histochem. Cytochem.49:1235-1243(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    14. 14.
      "The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum."
      Breckenridge D.G. , Nguyen M. , Kuppig S. , Reth M. , Shore G.C.
      Proc. Natl. Acad. Sci. U.S.A.99:4331-4336(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CASP8 ISOFORM 9
    15. 15.
      "The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B."
      Wang B. , Pelletier J. , Massaad M.J. , Herscovics A. , Shore G.C.
      Mol. Cell. Biol.24:2767-2778(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PTPLB
    16. 16.
      "Contiguous deletion of the X-linked adrenoleukodystrophy gene (ABCD1) and DXS1357E: a novel neonatal phenotype similar to peroxisomal biogenesis disorders."
      Corzo D. , Gibson W. , Johnson K. , Mitchell G. , LePage G. , Cox G.F. , Casey R. , Zeiss C. , Tyson H. , Cutting G.R. , Raymond G.V. , Smith K.D. , Watkins P.A. , Moser A.B. , Moser H.W. , Steinberg S.J.
      Am. J. Hum. Genet.70:1520-1531(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN CONTIGUOUS ABCD1/DXS1375E DELETION SYNDROME
    17. 17.
      "Bap31 is an itinerant protein that moves between the peripheral endoplasmic reticulum (ER) and a juxtanuclear compartment related to ER-associated Degradation."
      Wakana Y. , Takai S. , Nakajima K. , Tani K. , Yamamoto A. , Watson P. , Stephens D.J. , Hauri H.P. , Tagaya M.
      Mol. Biol. Cell19:1825-1836(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    18. 18.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    19. 19.
      "Mutations in BCAP31 cause a severe X-linked phenotype with deafness, dystonia, and central hypomyelination and disorganize the Golgi apparatus."
      Cacciagli P. , Sutera-Sardo J. , Borges-Correia A. , Roux J.C. , Dorboz I. , Desvignes J.P. , Badens C. , Delepine M. , Lathrop M. , Cau P. , Levy N. , Girard N. , Sarda P. , Boespflug-Tanguy O. , Villard L.
      Am. J. Hum. Genet.93:579-586(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN DDCH
    20. 20.
      "Structural and biophysical characterization of the cytoplasmic domains of human BAP29 and BAP31."
      Quistgaard E.M. , Low C. , Moberg P. , Guettou F. , Maddi K. , Nordlund P.
      PLoS ONE8:E71111-E71111(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 168-233;SUBUNIT;COILED-COIL
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